Sjögren syndrome

Diabetes mellitus type 2

P

Patients number

127

127

Women

120 (94.5%)

120 (94.5%)

Median age and interquartile range

60 years (47 - 71)

62 years (52 - 71)

Underlying diseases¹

•  Cirrhosis

3 (2.4%)

3 (2.4%)

NS

•  Pulmonary disease (COPD, bronchiectasis or fibrosis)

15 (11.8%)

9 (7.1%)

NS

•  Heart disease (including hypertension)

43 (33.9%)

81 (63.8%)

P < 0.001

•  Cancer (non-lymphomas)

16 (12.6%)

4 (3.1%)

P = 0.009

•  Chronic renal disease (stage > 3)

4 (3.1%)

4 (3.1%)

NS

•  Obesity

3 (2.4%)

12 (9.4%)

P = 0.030

Deaths during the study period

33 (25.9%)

25 (19.7%)

NS

Follow-up time in days²: mean and median

5114.9 (SD ± 1349.4); 5751 (IQ 5751-5751)

5360.9 (SD ± 977.9) 5751 (IQ 5751-5751)

NS

Number of laboratory requests³ per patient: mean and median

73.7 (SD ± 60);

60 (IQ 36-98)

40.3 (SD ± 48.8);

28 (IQ 14-48)

P < 0.001

Number of microbiological cultures requested per patient: mean and median

13.9 (SD ± 16.8);

9 (IQ 4-17)

5.9 (SD ± 12);

2 (IQ 1-7)

P < 0.001

Respiratory samples and/or sterile samples cultured: mean and median

3.7(SD ± 6.4);

2 (IQ 0-4)

1.2(SD ± 4);

0 (IQ 0-1)

P < 0.001

23-valent pneumococcal vaccine

4 (3.1%)

3 (2.4%)

NS

Patients with pneumococcal diseases

12 (9.4%)

2 (1.6%)

P = 0.011; RR 6

(95% CI 1.4 to 26.3)

Respiratory and/or invasive pneumococcal episodes

19 (15%)

2 (1.6%)

P < 0.001; RR 9.5

(95% CI 2.3 to 40)

Patients with Staphylococcus aureus infections

20 (15.7%)

10 (7.9%)

NS (P = 0.08)

Patients with Streptococcus agalactiae infections

10 (7.9%)

4 (3.1%)

NS